Subject: Royal Society Review Date: Fri, 30 Apr 1999 15:47:21 +0100 From: Rebecca.Bowden@royalsoc.ac.uk To: a.pusztai@freenet.co.uk Dear Professor Pusztai, I have received the following queries from reviewers of the information regarding possible toxicity of GM potatoes which I would be very grateful for clarification on. I have also faxed the questions to the Rowett Research Institute for their response. If you think that I should address these queries to someone else please let me know. I would be very grateful if you could acknowledge receipt of this e mail as our computer system has been experiencing some problems lately. I would also be very grateful if I could have your views on the queries as soon as possible so that I can feed them back to our reviewers. Many thanks for your assistance. Yours, Rebecca Dr Rebecca Bowden Senior Project Manager, Science Policy The Royal Society, 6 Carlton House Terrace, London, SW1Y 5AG Tel: (171) 451 2588 Fax: (171) 451 2692 e mail: rebecca.bowden@royalsoc.ac.uk e mail (home): bec@angelrdc.demon.co.uk website: http://www.royalsoc.ac.uk Registered Charity Number 207043 Questions from Reviewers of information on possible toxicity of GM Potatoes With regard to the document 'Response of the Audit Committee to Dr Arpad Pusztai's Alternative Report of 22 October 1998' 1. Please could you clarify if the statistical analyses relate to the control data - was the GM potato outcome significantly different from the relative comparison group? For example, in table 2 of the above document, was the final BW in the last column (raw potato, transgenic 3) significantly different from raw potato (parent) and spike 3 and/or raw potato (parent) 3. If so, this suggests a specific effect of the transgene and its construct to increase body weight. 2. In Table 1 of the above document please clarify what the Control consisted of. ----------------------------------------------------- -----------------------------------------------------